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Alkaloid synthesis

Back to basics

Nature Chemistry volume 2, pages 807–808 (2010)Cite this article

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Taking inspiration from a proposed biosynthetic sequence, a cascade of simple reactions leads to an efficient synthesis of the alkaloid natural product (+)-fastigiatine.

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Figure 1: The total synthesis of (+)-fastigiatine.

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Authors and Affiliations

  1. Brad M. Loertscher and Steven L. Castle are in the Department of Chemistry and Biochemistry, Brigham Young University, Provo, Utah 84602, USA.,

    Brad M. Loertscher & Steven L. Castle

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  1. Brad M. Loertscher
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  2. Steven L. Castle
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Correspondence to Steven L. Castle.

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Loertscher, B., Castle, S. Back to basics. Nature Chem 2, 807–808 (2010). https://doi.org/10.1038/nchem.851

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