A series of scanning probe microscopy experiments combined with density functional theory calculations have now been used to unambiguously determine the structure of a marine natural product. Can this method become generally useful for the determination of the structure of natural products?
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Blunt, J. Molecules under the microscope. Nature Chem 2, 799–800 (2010). https://doi.org/10.1038/nchem.849
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DOI: https://doi.org/10.1038/nchem.849