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Reaction kinetics

Catalysis without a catalyst

Can two identical reactors with the same concentrations, under identical physical conditions, have reaction rates that differ by a factor of a thousand? A study now shows that, although not true in uncrowded environments, a reactant's starting point makes a large difference to reaction kinetics in identically crowded systems, such as cellular nuclei.

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Figure 1: A random race through crowded space: here reactant 1 starts at site S1 and reactant 2 at S2.

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Kopelman, R. Catalysis without a catalyst. Nature Chem 2, 430–431 (2010). https://doi.org/10.1038/nchem.675

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