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Supramolecular capsules

Under control

Macrocyclic compounds can serve as hosts for smaller organic molecules, but precise control over the uptake and release of the guests remains challenging. Now, a host–guest system has been built that responds to the addition of metal ions, showing promise for drug-delivery applications.

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Figure 1: Supramolecular capsule formation between cucurbit[7]uril and thioflavin T, and the effect of metal ions.

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Nau, W. Under control. Nature Chem 2, 248–250 (2010). https://doi.org/10.1038/nchem.605

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