An enzyme that is unusually tolerant of a truly broad range of substrates can catalyse aldol-type chemistry on sugars in which the various hydroxyl groups are protected. The new methodology combines some of the most important advantages of enzyme and small-molecule catalysis.
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Davis, B. Sweet flexibility. Nature Chem 2, 85–86 (2010). https://doi.org/10.1038/nchem.529
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DOI: https://doi.org/10.1038/nchem.529
