Synthetic procedures for making nanoparticles often result in samples that contain a range of different particle sizes. By using hollow self-assembled metal–organic spheres as templates, however, it is possible to make silica nanoparticles with uniform shapes and sizes in a precisely controlled fashion.
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Breiner, B., Nitschke, J. Producing 'perfect' particles. Nature Chem 2, 6–7 (2010). https://doi.org/10.1038/nchem.493