Organic synthesis

New uses for old building blocks

New methodology that couples together carbonyl compounds with boronic acids shows much promise for synthesis owing to ease of access of the building blocks, functional group tolerance and broad scope of the reaction.

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Figure 1: Construction of complex chemical compounds from simple building blocks.
Figure 2: Successful and unsuccessful reactions of diazoesters with boron derivatives.

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Aggarwal, V. New uses for old building blocks. Nature Chem 1, 433–434 (2009). https://doi.org/10.1038/nchem.346

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