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Organometallic chemistry

A shortcut to molecular complexity

A unique transformation for the site-selective cleavage of one C–C single bond and two C–H bonds in sequence has now been developed. This enables a simple carbon skeleton to be reorganized into a significantly more complex form with remarkable efficiency.

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Figure 1: Catalytic cycle proposed by Lautens and co-workers.

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Correspondence to Masahiro Murakami.

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Murakami, M., Ishida, N. A shortcut to molecular complexity. Nature Chem 9, 298–299 (2017). https://doi.org/10.1038/nchem.2750

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