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Bioanalytical chemistry

Protein oligomers frozen in time

Nature Chemistry volume 1, pages 257258 (2009) | Download Citation

Subjects

The size and shape of amyloid-β protein assemblies have been studied using electrospray-ionization ion-mobility mass spectrometry, and the protein tetramers and dodecamers have been identified as an important oligomerization state in the development of neurodegenerative disease.

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Author information

Affiliations

  1. David E. Clemmer and Stephen J. Valentine are in the Department of Chemistry, Indiana University, Bloomington, Indiana 47405, USA.  clemmer@indiana.edu

    • David E. Clemmer
    •  & Stephen J. Valentine

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DOI

https://doi.org/10.1038/nchem.264

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