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Organometallic chemistry

A new metathesis

Carbonyls and alkenes, two of the most common functional groups in organic chemistry, generally do not react with one another. Now, a simple Lewis acid has been shown to catalyse metathesis between alkenes and ketones in a new carbonyl olefination reaction.

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Figure 1: Approaches for the carbonyl–olefin metathesis reaction.

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Correspondence to Eric N. Jacobsen.

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Hennessy, E., Jacobsen, E. A new metathesis. Nature Chem 8, 741–742 (2016). https://doi.org/10.1038/nchem.2581

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