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Molecular self-assembly

Searching sequence space

Short peptides are among the most intriguing building blocks in nanotechnology, but it would be very challenging to experimentally study the properties of large numbers of different sequences. Now, a computational analysis of all 8,000 possible tripeptides has been used to identify those with interesting self-assembly behaviour.

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Figure 1: Identification of aggregation-prone tripeptide motifs.

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Correspondence to Ehud Gazit.

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Gazit, E. Searching sequence space. Nature Chem 7, 14–15 (2015). https://doi.org/10.1038/nchem.2140

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