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Enzymatic C–H bond activation

Using push to get pull

Nature Chemistry volume 6, pages 8991 (2014) | Download Citation

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Cytochrome P450 enzymes are able to oxidize substrates that are more inert than their own surrounding protein framework. Now, a quantitative understanding has emerged as to how the enzymes accomplish this remarkable feat.

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Author information

Affiliations

  1. John T. Groves is in the Department of Chemistry at Princeton University, Princeton, New Jersey 08544, USA

    • John T. Groves

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Correspondence to John T. Groves.

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DOI

https://doi.org/10.1038/nchem.1855

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