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C–H Activation

A surrogate for selectivity

Metal-coordinating groups are widely used to direct C–H functionalization. Now the combination of an alkene hydrosilylation, C–H activation and C–Si oxidation has been used to achieve a formal 1,4-dioxygenation of alkenes.

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Figure 1: Selective C–H functionalization using surrogate directing groups.
Figure 2

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Correspondence to Eric M. Ferreira.

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Ferreira, E. A surrogate for selectivity. Nature Chem 6, 94–96 (2014). https://doi.org/10.1038/nchem.1851

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