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Chemical origins of life

Prebiotic RNA unstuck

Nature Chemistry volume 5, pages 360362 (2013) | Download Citation

Non-enzymatic copying of an RNA template is appealing as a transition from pre-life to an RNA world, but it has been difficult to demonstrate in the laboratory. Now, two separate studies focusing on RNA's backbone connectivity offer partial solutions to some of the problems raised with this hypothesis for the origin of life.

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Author information

Affiliations

  1. Armando Hernández is in the Department of Biochemistry and Molecular Biology and Joseph Piccirilli is in the Departments of Biochemistry and Molecular Biology, and Chemistry at the University of Chicago, 929 East 57th Street, Chicago, Illinois 60637, USA

    • Armando R. Hernández
    •  & Joseph A. Piccirilli

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Corresponding author

Correspondence to Joseph A. Piccirilli.

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DOI

https://doi.org/10.1038/nchem.1636

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