The direct observation and quantification of G-quadruplex structures formed from DNA in human cells during the cell cycle demonstrate the biological importance of these structures and point towards opportunities for targeting them with small-molecule drugs.
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Siddiqui-Jain, A., Hurley, L. Visualizing the quadruplex. Nature Chem 5, 153–155 (2013). https://doi.org/10.1038/nchem.1587
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DOI: https://doi.org/10.1038/nchem.1587
