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Molecular switches

Hydrazones double down on zinc

Molecular engineers have long relied on a single light-driven event or chemical input to induce structural changes in switching systems. By carefully designing two hydrazone-based switches, it has now been shown that a single metal-binding event can trigger a signalling cascade that results in the isomerization of two different molecules.

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Figure 1: Hydrazone-based switches.

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Correspondence to Shawn C. Burdette.

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Burdette, S. Hydrazones double down on zinc. Nature Chem 4, 695–696 (2012). https://doi.org/10.1038/nchem.1438

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