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Carbohydrate recognition

A minimalistic approach to binding

Synthetic receptors with properties resembling those of carbohydrate-binding proteins are known, but they are structurally rather complex. Elaborate structures are, however, not always required to bind carbohydrates in water — much simpler compounds can be just as effective.

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Figure 1: A schematic representation of the lectin wheat-germ agglutinin8 and chemical structures of the synthetic lectins developed in the Davis group.


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Correspondence to Stefan Kubik.

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Kubik, S. A minimalistic approach to binding. Nature Chem 4, 697–698 (2012).

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