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Asymmetric catalysis

Correlating sterics in catalysis

Recognizing that an analogy can be drawn between steric effects in drug discovery and asymmetric catalysis has led to a powerful technique that can explain and potentially predict the outcome of asymmetric reactions.

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Figure 1: Complexity compounded.

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Correspondence to Scott J. Miller.

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Miller, S. Correlating sterics in catalysis. Nature Chem 4, 344–345 (2012). https://doi.org/10.1038/nchem.1339

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