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Protein thermodynamics

Are native proteins metastable?

Nature Chemistry volume 3, pages 910911 (2011) | Download Citation

Thermodynamic measurements show that the most stable structural form of a number of proteins under cellular conditions is fibrillar, implying that their functional states may only be metastable.

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Author information

Affiliations

  1. D. Thirumalai and G. Reddy are in the Institute for Physical Science and Technology, University of Maryland, College Park, Maryland 20742, USA

    • D. Thirumalai
    •  & G. Reddy

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Correspondence to D. Thirumalai.

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DOI

https://doi.org/10.1038/nchem.1207

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