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Reversible covalent chemistry

Alcohols in the mix

Nature Chemistry volume 3, pages 909910 (2011) | Download Citation

The scope of dynamic combinatorial chemistry is somewhat limited by the small number of predictably reversible reactions. Now, secondary alcohols are shown to quickly and reversibly react with iminium ions to form hemiaminal ethers, opening up opportunites for their use in the construction of complex — and functional — dynamic architectures.

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  1. Ognjen Š. Miljanić is at the Department of Chemistry, University of Houston, Houston, Texas 77204-5003, USA

    • Ognjen Š. Miljanić

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Correspondence to Ognjen Š. Miljanić.

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https://doi.org/10.1038/nchem.1203

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