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Natural product synthesis

Making nematodes nervous

A highly inventive route for the synthesis of a key substance that stimulates potato cyst nematodes to hatch has been developed. This discovery has potential to impact food supplies, as treatment of crops with this compound could alleviate the devastating effect of these parasites.

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Figure 1: Critical hatch-stimulating substances.

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Correspondence to Scott A Snyder.

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Snyder, S. Making nematodes nervous. Nature Chem 3, 422–423 (2011). https://doi.org/10.1038/nchem.1059

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