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F-actin organizes the nucleus

Nature Cell Biology volume 19, pages 13861388 (2017) | Download Citation

After mitosis, the nucleus must be rebuilt and chromatin decondensed to permit interphase genomic functions, but decondensation mechanisms are poorly understood. Now, the traditional cytoskeletal protein actin is shown to form transient nuclear filaments that are required for chromatin decondensation and nuclear expansion at mitotic exit.

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Author information

Affiliations

  1. Henna M. Moore and Maria K. Vartiainen are at the Institute of Biotechnology, University of Helsinki, Helsinki, Finland Viikinkaari 5, 00014 Helsinki, Finland

    • Henna M. Moore
    •  & Maria K. Vartiainen

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Competing interests

The authors declare no competing financial interests.

Corresponding author

Correspondence to Maria K. Vartiainen.

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DOI

https://doi.org/10.1038/ncb3650

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