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Capturing endosomal vesicles at the Golgi

Nature Cell Biology volume 19, pages 1384–1386 (2017)Cite this article

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Membrane trafficking specificity between distinct compartments ensures that cargo proteins and lipids are delivered to their target organelle. However, accurate recognition of cargo carriers by tethering factors on target membranes is poorly understood. TBC1D23 is now identified as an adaptor that links endosome-derived vesicles with golgins at the trans-Golgi.

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Figure 1: Ectopic golgin-BirA* fusion identifies binding partner.
Figure 2: TBC1D23 links golgins to the WASH complex on endosomal vesicles.

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Authors and Affiliations

  1. Department of Molecular Biology and Genetics, Weill Institute for Cell and Molecular Biology, Cornell University, Ithaca, 14853, New York, USA

    J. Christopher Fromme

  2. Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, 364 Plantation Street, Worcester, 01605, Massachusetts, USA

    Mary Munson

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  1. J. Christopher Fromme
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Correspondence to Mary Munson.

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Fromme, J., Munson, M. Capturing endosomal vesicles at the Golgi. Nat Cell Biol 19, 1384–1386 (2017). https://doi.org/10.1038/ncb3649

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