Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

The skinny on obesity and cancer

Nature Cell Biology volume 19, pages 887–888 (2017)Cite this article

Subjects

Obesity now rivals smoking as one of the leading preventable causes of cancer. Obesity-associated neutrophilia is now shown to enhance breast cancer metastasis and to be reversible through dietary modification and weight loss.

This is a preview of subscription content, access via your institution

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

Figure 1: The effects of obesity and weight loss on breast cancer metastasis.

References

  1. Calle, E. E. & Kaaks, R. Nat. Rev. Cancer 4, 579–591 (2004).

    Article  CAS  Google Scholar 

  2. Ligibel, J. A. et al. J. Clin. Oncol. 32, 3568–3574 (2014).

    Article  Google Scholar 

  3. Coussens, L. M., Zitvogel, L. & Palucka, A. K. Science 339, 286–291 (2013).

    Article  CAS  Google Scholar 

  4. McAllister, S. S. & Weinberg, R. A. Nat. Cell Biol. 16, 717–727 (2014).

    Article  CAS  Google Scholar 

  5. Peinado, H. et al. Nat. Rev. Cancer 17, 302–317 (2017).

    Article  CAS  Google Scholar 

  6. Quail, D. F. et al. Nat. Cell Biol. 19, 974–987 (2017).

    Article  CAS  Google Scholar 

  7. Osman, M. A. & Hennessy, B. T. Clin. Med. Insights Oncol. 9, 105–112 (2015).

    Article  Google Scholar 

  8. Weigelt, B., Peterse, J. L. & van 't Veer, L. J. B Nat. Rev. Cancer 5, 591–602 (2005).

    Article  CAS  Google Scholar 

  9. Zhang, Y. et al. Nature 372, 425–432 (1994).

    Article  CAS  Google Scholar 

  10. Alemán, J. O. et al. J. Endocr. Soc. 1, 625–637 (2017).

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Division of Hematology, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, 02115, Massachusetts, USA

    Jaclyn Sceneay & Sandra S. McAllister

  2. Broad Institute of Harvard and MIT, Cambridge, 02142, Massachusetts, USA

    Sandra S. McAllister

  3. Harvard Stem Cell Institute, Cambridge, 02138, Massachusetts, USA

    Sandra S. McAllister

Authors
  1. Jaclyn Sceneay
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Sandra S. McAllister
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Sandra S. McAllister.

Ethics declarations

Competing interests

The authors declare no competing financial interests.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Sceneay, J., McAllister, S. The skinny on obesity and cancer. Nat Cell Biol 19, 887–888 (2017). https://doi.org/10.1038/ncb3583

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/ncb3583

This article is cited by

Search

Advanced search

Quick links

Nature Briefing: Cancer

Sign up for the Nature Briefing: Cancer newsletter — what matters in cancer research, free to your inbox weekly.

Get what matters in cancer research, free to your inbox weekly. Sign up for Nature Briefing: Cancer