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Haematopoietic stem cells show their true colours

Nature Cell Biology volume 19, pages 1012 (2017) | Download Citation

Delineating the behaviour of haematopoietic stem cells (HSCs) in vivo has thus far proven challenging. Two studies in zebrafish and mouse models now track HSCs in vivo using fate mapping with multicolour approaches to provide further insights into clonal events that regulate blood development, HSC function and differentiation during homeostasis and stress conditions.

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Affiliations

  1. Trista E. North is at the Beth Israel Deaconess Medical Center, Department of Pathology, Harvard Medical School, Harvard Stem Cell Institute, CLS 536, 3 Blackfan Circle, Boston, Massachusetts 02115, USA

    • Trista E. North
  2. Wolfram Goessling is at the Brigham and Women's Hospital, Genetics and Gastroenterology Division, Harvard Medical School, Harvard Stem Cell Institute, NRB 458, 77 Avenue Louis Pasteur, Boston, Massachusetts 02215, USA

    • Wolfram Goessling

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Competing interests

The authors declare no competing financial interests.

Corresponding authors

Correspondence to Trista E. North or Wolfram Goessling.

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DOI

https://doi.org/10.1038/ncb3459

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