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Multiple cilia suppress tumour formation

Primary cilia are cellular structures that have important functions in development and disease. The suppression of multiciliate differentiation of choroid plexus precursors, and maintenance of a single primary cilium by Notch1, is now shown to be involved in choroid plexus tumour formation.

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Figure 1: Notch1 activation suppresses multiciliate differentiation in choroid plexus epithelium.


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Correspondence to Charles Eberhart.

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Eberhart, C. Multiple cilia suppress tumour formation. Nat Cell Biol 18, 368–369 (2016).

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