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Multiple cilia suppress tumour formation

Nature Cell Biology volume 18, pages 368–369 (2016)Cite this article

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Primary cilia are cellular structures that have important functions in development and disease. The suppression of multiciliate differentiation of choroid plexus precursors, and maintenance of a single primary cilium by Notch1, is now shown to be involved in choroid plexus tumour formation.

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Figure 1: Notch1 activation suppresses multiciliate differentiation in choroid plexus epithelium.

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  1. Departments of Pathology, Charles Eberhart is at the Johns Hopkins University School of Medicine, Ophthalmology and Oncology, Baltimore, Maryland 21205, USA,

    Charles Eberhart

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  1. Charles Eberhart
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Correspondence to Charles Eberhart.

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Eberhart, C. Multiple cilia suppress tumour formation. Nat Cell Biol 18, 368–369 (2016). https://doi.org/10.1038/ncb3331

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