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STIMATE reveals a STIM1 transitional state

Nature Cell Biology volume 17, pages 12321234 (2015) | Download Citation

Decreases in endoplasmic reticulum calcium content are sensed by resident STIM proteins, which can activate plasma membrane Orai channels to facilitate Ca2+ entry. The role of STIMATE, a previously unknown component of the store-operated calcium entry complex, has now been identified and defined.

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Author information

Affiliations

  1. Robert Hooper and Jonathan Soboloff are at the Fels Institute for Cancer Research and Molecular Biology, Temple University School of Medicine, Philadelphia, Pennsylvania 19140, USA

    • Robert Hooper
    •  & Jonathan Soboloff
  2. J.S. is also in the Department of Medical Genetics & Molecular Biochemistry, Temple University School of Medicine, Philadelphia, Pennsylvania 19140, USA

    • Jonathan Soboloff

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  1. Search for Robert Hooper in:

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Competing interests

The authors declare no competing financial interests.

Corresponding author

Correspondence to Jonathan Soboloff.

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DOI

https://doi.org/10.1038/ncb3245

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