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Linking primary and metastatic tumour re-initiation

Nature Cell Biology volume 17, pages 542543 (2015) | Download Citation

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Whether the cancer cells responsible for the growth of primary tumours are also able to re-initiate tumour growth after seeding to distant organs is unclear. The characterization of breast cancer cells with both of these attributes now identifies the functional and molecular determinants necessary to mediate primary tumour formation and re-initiation at the secondary site.

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Author information

Affiliations

  1. Barzin Y. Nabet and Andy J. Minn are at the Abramson Family Cancer Research Institute, Department of Radiation Oncology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104-6160, USA

    • Barzin Y. Nabet
    •  & Andy J. Minn

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Competing interests

The authors declare no competing financial interests.

Corresponding author

Correspondence to Andy J. Minn.

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DOI

https://doi.org/10.1038/ncb3173

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