Eaton, S. & Jülicher, F. Cell flow and tissue polarity patterns. Curr. Opin. Genet. Dev. 21, 747–752 (2011).
Goodrich, L. V. & Strutt, D. Principles of planar polarity in animal development. Development 138, 1877–1892 (2011).
McNeill, H. Planar cell polarity: keeping hairs straight is not so simple. Cold Spring Harb. Perspect. Biol. 2, a003376 (2010).
Devenport, D. & Fuchs, E. Planar polarization in embryonic epidermis orchestrates global asymmetric morphogenesis of hair follicles. Nat. Cell Biol. 10, 1257–1268 (2008).
Guo, N., Hawkins, C. & Nathans, J. Frizzled6 controls hair patterning in mice. Proc. Natl Acad. Sci. USA 101, 9277–9281 (2004).
Aigouy, B. et al. Cell flow reorients the axis of planar polarity in the wing epithelium of Drosophila. Cell 142, 773–786 (2010).
Matis, M. & Axelrod, J. D. Regulation of PCP by the Fat signaling pathway. Genes Dev. 27, 2207–2220 (2013).
Luxenburg, C., Pasolli, H. A., Williams, S. E. & Fuchs, E. Developmental roles for Srf, cortical cytoskeleton and cell shape in epidermal spindle orientation. Nat. Cell Biol. 13, 203–214 (2011).
Fujibuchi, T. et al. AIP1/WDR1 supports mitotic cell rounding. Biochem. Biophys. Res. Commun. 327, 268–275 (2005).
Chen, Q., Courtemanche, N. & Pollard, T. D. Aip1 promotes actin filament severing by cofilin and regulates the constriction of the cytokinetic contractile ring. J. Biol. Chem. 290, 2289–2300 (2014).
Aizawa, H. et al. Hyperosmotic stress-induced reorganization of actin bundles in Dictyostelium cells over-expressing cofilin. Genes Cells 4, 311–324 (1999).
Augustine, R. C., Pattavina, K. A., Tuzel, E., Vidali, L. & Bezanilla, M. Actin interacting protein1 and actin depolymerizing factor drive rapid actin dynamics in Physcomitrella patens. Plant Cell 23, 3696–3710 (2011).
Chu, D. et al. AIP1 acts with cofilin to control actin dynamics during epithelial morphogenesis. Development 139, 3561–3571 (2012).
Lin, M-C., Galletta, B. J., Sept, D. & Cooper, J. A. Overlapping and distinct functions for cofilin, coronin and Aip1 in actin dynamics in vivo. J. Cell Sci. 123, 1329–1342 (2010).
Mohri, K. & Ono, S. Actin filament disassembling activity of Caenorhabditis elegans actin-interacting protein 1 (UNC-78) is dependent on filament binding by a specific ADF/cofilin isoform. J. Cell Sci. 116, 4107–4118 (2003).
Okada, K., Obinata, T. & Abe, H. XAIP1: a Xenopus homologue of yeast actin interacting protein 1 (AIP1), which induces disassembly of actin filaments cooperatively with ADF/cofilin family proteins. J. Cell Sci. 112 (Pt 10), 1553–1565 (1999).
Rodal, A. A., Tetreault, J. W., Lappalainen, P., Drubin, D. G. & Amberg, D. C. Aip1p interacts with cofilin to disassemble actin filaments. J. Cell Biol. 145, 1251–1264 (1999).
Kile, B. T. et al. Mutations in the cofilin partner Aip1/Wdr1 cause autoinflammatory disease and macrothrombocytopenia. Blood 110, 2371–2380 (2007).
Beronja, S., Livshits, G., Williams, S. & Fuchs, E. Rapid functional dissection of genetic networks via tissue-specific transduction and RNAi in mouse embryos. Nat. Med. 16, 821–827 (2010).
Curtin, J. A. et al. Mutation of celsr1 disrupts planar polarity of inner ear hair cells and causes severe neural tube defects in the mouse. Curr. Biol. 13, 1129–1133 (2003).
Kibar, Z. et al. Ltap, a mammalian homolog of Drosophila Strabismus/Van Gogh, is altered in the mouse neural tube mutant Loop-tail. Nat. Genet. 28, 251–255 (2001).
Chen, X. & Macara, I. G. Par-3 mediates the inhibition of LIM kinase 2 to regulate cofilin phosphorylation and tight junction assembly. J. Cell Biol. 172, 671–678 (2006).
Michelot, A. et al. Actin filament elongation in Arp2/3-derived networks is controlled by three distinct mechanisms. Dev. Cell 24, 182–195 (2013).
Nadkarni, A. V. & Brieher, W. M. Aip1 destabilizes cofilin-saturated actin filaments by severing and accelerating monomer dissociation from ends. Curr. Biol. 24, 2749–2757 (2014).
Ikeda, S. et al. Aberrant actin cytoskeleton leads to accelerated proliferation of corneal epithelial cells in mice deficient for destrin (actin depolymerizing factor). Hum. Mol. Genet. 12, 1029–1037 (2003).
Smith, R. S. et al. Corn1: a mouse model for corneal surface disease and neovascularization. Invest. Ophthalmol. Vis. Sci. 37, 397–404 (1996).
Agnew, B. J., Minamide, L. S. & Bamburg, J. R. Reactivation of phosphorylated actin depolymerizing factor and identification of the regulatory site. J. Biol. Chem. 270, 17582–17587 (1995).
Nagaoka, R., Abe, H. & Obinata, T. Site-directed mutagenesis of the phosphorylation site of cofilin: its role in cofilin-actin interaction and cytoplasmic localization. Cell. Motil. Cytoskeleton 35, 200–209 (1996).
Kiuchi, T., Ohashi, K., Kurita, S. & Mizuno, K. Cofilin promotes stimulus-induced lamellipodium formation by generating an abundant supply of actin monomers. J. Cell Biol. 177, 465–476 (2007).
Mahaffey, J. P., Grego-Bessa, J., Liem, K. F. & Anderson, K. V. Cofilin and Vangl2 cooperate in the initiation of planar cell polarity in the mouse embryo. Development 140, 1262–1271 (2013).
Devenport, D., Oristian, D., Heller, E. & Fuchs, E. Mitotic internalization of planar cell polarity proteins preserves tissue polarity. Nat. Cell Biol. 13, 893–902 (2011).
Ren, N., Charlton, J. & Adler, P. N. The flare gene, which encodes the AIP1 protein of Drosophila, functions to regulate F-actin disassembly in pupal epidermal cells. Genetics 176, 2223–2234 (2007).
Shimada, Y., Yonemura, S., Ohkura, H., Strutt, D. & Uemura, T. Polarized transport of Frizzled along the planar microtubule arrays in Drosophila wing epithelium. Dev. Cell 10, 209–222 (2006).
Ross, A. J. et al. Disruption of Bardet-Biedl syndrome ciliary proteins perturbs planar cell polarity in vertebrates. Nat. Genet. 37, 1135–1140 (2005).
Reymann, A. C. et al. Actin network architecture can determine myosin motor activity. Science 336, 1310–1314 (2012).
Ono, K. & Ono, S. Two actin-interacting protein 1 isoforms function redundantly in the somatic gonad and are essential for reproduction in Caenorhabditis elegans. Cytoskeleton (Hoboken) 71, 36–45 (2014).
Yuan, B. et al. A cardiomyocyte-specific Wdr1 knockout demonstrates essential functional roles for actin disassembly during myocardial growth and maintenance in mice. Am. J. Pathol. 184, 1967–1980 (2014).
Rhee, J. M. et al. In vivo imaging and differential localization of lipid-modified GFP-variant fusions in embryonic stem cells and mice. Genesis 44, 202–218 (2006).
Hutson, M. S. et al. Forces for morphogenesis investigated with laser microsurgery and quantitative modeling. Science 300, 145–149 (2003).
Farhadifar, R., Röper, J-C., Aigouy, B., Eaton, S. & Jülicher, F. The influence of cell mechanics, cell–cell interactions, and proliferation on epithelial packing. Curr. Biol. 17, 2095–2104 (2007).
Fernandez-Gonzalez, R., Simoes, S. D. E. M., Röper, J. C., Eaton, S. & Zallen, J. A. Myosin II dynamics are regulated by tension in intercalating cells. Dev. Cell 17, 736–743 (2009).
Straight, A. F. et al. Dissecting temporal and spatial control of cytokinesis with a myosin II inhibitor. Science 299, 1743–1747 (2003).
Ishizaki, T. et al. Pharmacological properties of Y-27632, a specific inhibitor of rho-associated kinases. Mol. Pharmacol. 57, 976–983 (2000).
Bubb, M. R., Senderowicz, A. M., Sausville, E. A., Duncan, K. L. & Korn, E. D. Jasplakinolide, a cytotoxic natural product, induces actin polymerization and competitively inhibits the binding of phalloidin to F-actin. J. Biol. Chem. 269, 14869–14871 (1994).
Heisenberg, C. P. & Bellaïche, Y. Forces in tissue morphogenesis and patterning. Cell 153, 948–962 (2013).
Guillot, C. & Lecuit, T. Mechanics of epithelial tissue homeostasis and morphogenesis. Science 340, 1185–1189 (2013).
Arber, S. et al. Regulation of actin dynamics through phosphorylation of cofilin by LIM-kinase. Nature 393, 805–809 (1998).
Yang, N. et al. Cofilin phosphorylation by LIM-kinase 1 and its role in Rac-mediated actin reorganization. Nature 393, 809–812 (1998).
Moriyama, K. & Yahara, I. The actin-severing activity of cofilin is exerted by the interplay of three distinct sites on cofilin and essential for cell viability. Biochem. J. 365, 147–155 (2002).
Wiggan, O., Shaw, A. E., DeLuca, J. G. & Bamburg, J. R. ADF/cofilin regulates actomyosin assembly through competitive inhibition of myosin II binding to F-actin. Dev. Cell 22, 530–543 (2012).