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Merlin's wizardry guides cohesive migration

Nature Cell Biology volume 17, pages 212213 (2015) | Download Citation

Cells often migrate in tightly connected groups with coordinated movement and polarity. The collective migration of epithelial cell sheets is now shown to be mediated by a signalling axis that involves the merlin tumour-suppressor protein, the tight-junction-associated angiomotin–Rich1 complex and the Rac1 small GTPase.

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Author information

Affiliations

  1. Ansgar Zoch and Helen Morrison are at the Leibniz Institute for Age Research, Fritz Lipmann Institute, 07745 Jena, Germany

    • Ansgar Zoch
    •  & Helen Morrison

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Competing interests

The authors declare no competing financial interests.

Corresponding author

Correspondence to Helen Morrison.

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DOI

https://doi.org/10.1038/ncb3126

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