Cells often migrate in tightly connected groups with coordinated movement and polarity. The collective migration of epithelial cell sheets is now shown to be mediated by a signalling axis that involves the merlin tumour-suppressor protein, the tight-junction-associated angiomotin–Rich1 complex and the Rac1 small GTPase.
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Zoch, A., Morrison, H. Merlin's wizardry guides cohesive migration. Nat Cell Biol 17, 212–213 (2015). https://doi.org/10.1038/ncb3126
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DOI: https://doi.org/10.1038/ncb3126
