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Control of ciliation in embryogenesis

Nature Cell Biology volume 17, pages 109111 (2015) | Download Citation

The protrusion of cilia into extracellular space provides cells with sensors of localized environmental cues that include fluid flow, mechanical force and important growth factors such as Hedgehog. Live imaging has now captured the initial appearance of cilia during embryogenesis, and defined lineage-specific determinants that restrict extra-embryonal ciliogenesis.

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Author information

Affiliations

  1. Anna S. Nikonova and Erica A. Golemis are in the Program in Molecular Therapeutics, Fox Chase Cancer Center, Philadelphia, Pennsylvania 19111, USA

    • Anna S. Nikonova
    •  & Erica A. Golemis

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Competing interests

The authors declare no competing financial interests.

Corresponding author

Correspondence to Erica A. Golemis.

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DOI

https://doi.org/10.1038/ncb3103

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