The protrusion of cilia into extracellular space provides cells with sensors of localized environmental cues that include fluid flow, mechanical force and important growth factors such as Hedgehog. Live imaging has now captured the initial appearance of cilia during embryogenesis, and defined lineage-specific determinants that restrict extra-embryonal ciliogenesis.
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Nikonova, A., Golemis, E. Control of ciliation in embryogenesis. Nat Cell Biol 17, 109–111 (2015). https://doi.org/10.1038/ncb3103
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DOI: https://doi.org/10.1038/ncb3103
