ABCC4 is a member of the ATP-binding cassette transporter family known to transport prostaglandin E2 and other molecules across cellular membranes. A mutation in ABCC4 is now shown to cause defects in ciliogenesis, revealing a role for prostaglandin signalling in regulating cilia dynamics.
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Barbry, P., Zaragosi, LE. An ABC of ciliogenesis. Nat Cell Biol 16, 826–827 (2014). https://doi.org/10.1038/ncb3034
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DOI: https://doi.org/10.1038/ncb3034
