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Hi-TEC reprogramming for organ regeneration

Nature Cell Biology volume 16, pages 824825 (2014) | Download Citation

The induction of cell reprogramming by transcription factors into alternative cell fates opens new avenues for regenerative medicine. Thymic epithelial cells that were obtained from fibroblasts by Foxn1 overexpression support the formation of an ectopic thymus following transplantation.

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Author information

Affiliations

  1. Bruno Di Stefano and Thomas Graf are at the Gene Regulation, Stem Cells and Cancer Programme, Centre for Genomic Regulation and Universitat Pompeu Fabra, Dr Aiguader 88, 08003 Barcelona, Spain

    • Bruno Di Stefano
    •  & Thomas Graf
  2. Thomas Graf is also at Institució Catalana de Recerca i Estudis Avançats (ICREA), Pg Lluis Companys 23, 08010 Barcelona, Spain

    • Thomas Graf

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Competing interests

The authors declare no competing financial interests.

Corresponding authors

Correspondence to Bruno Di Stefano or Thomas Graf.

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DOI

https://doi.org/10.1038/ncb3032

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