The induction of cell reprogramming by transcription factors into alternative cell fates opens new avenues for regenerative medicine. Thymic epithelial cells that were obtained from fibroblasts by Foxn1 overexpression support the formation of an ectopic thymus following transplantation.
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Di Stefano, B., Graf, T. Hi-TEC reprogramming for organ regeneration. Nat Cell Biol 16, 824–825 (2014). https://doi.org/10.1038/ncb3032
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DOI: https://doi.org/10.1038/ncb3032
