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The multiple talents of kinesin-8

Multiple activities cooperate to determine the architecture of the mitotic spindle. Kip3 is a kinesin-8 motor protein in budding yeast that acts as a microtubule depolymerase. Now Kip3 is shown to also crosslink and slide antiparallel microtubules, providing additional insights into how kinesin-8 motors control spindle integrity.

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Figure 1: Kip3 domain structure and properties.

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Correspondence to Thomas Surrey.

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Roostalu, J., Surrey, T. The multiple talents of kinesin-8. Nat Cell Biol 15, 889–891 (2013). https://doi.org/10.1038/ncb2820

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