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p73 keeps metabolic control in the family

Nature Cell Biology volume 15, pages 891893 (2013) | Download Citation

The transcription factor p73, a close relative of p53, has complex yet poorly understood roles in tumorigenesis. TAp73, a p73 variant, has now been shown to promote cancer cell proliferation by regulating glucose metabolism to control cellular biosynthetic pathways and antioxidant capacity.

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Author information

Affiliations

  1. Louise Fets and Dimitrios Anastasiou are in the Division of Physiology and Metabolism, MRC National Institute for Medical Research, The Ridgeway, London NW7 1AA, UK

    • Louise Fets
    •  & Dimitrios Anastasiou

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Competing interests

The authors declare no competing financial interests.

Corresponding author

Correspondence to Dimitrios Anastasiou.

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DOI

https://doi.org/10.1038/ncb2810

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