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The amorphous pericentriolar cloud takes shape

Nature Cell Biology volume 14, pages 1126–1128 (2012)Cite this article

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The pericentriolar material (PCM), the microtubule-organizing component of the centrosome, contains a multitude of proteins and is commonly described as an amorphous cloud surrounding the centrioles. However, the days of the PCM as an unstructured matrix are numbered. Using super-resolution microscopy, several reports have now revealed remarkable domain organization within the PCM.

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Figure 1: Mitotic spindle in the egg of Ascaris megalocephala bivalens.
Figure 2: Organization of the PCM at human centrosomes.

References

  1. Luders, J. & Stearns, T. Nat. Rev. Mol. Cell Biol. 8, 161–167 (2007).

    Article  Google Scholar 

  2. Lawo, S., Hasegan, M., Gupta, G. D. & Pelletier, L. Nat. Cell Biol. 14, 1148–1158 (2012).

    Article  CAS  Google Scholar 

  3. Mennella, V. et al. Nat. Cell Biol. 14, 1159–1168 (2012).

    Article  CAS  Google Scholar 

  4. Fu, J. & Glover, D. M. Open Biol. 2, 120104 (2012).

    Article  Google Scholar 

  5. Sonnen, K. F., Schermelleh, L., Leonhardt, H. & Nigg, E. A. Biol. Open 1, 965–976 (2012).

    Article  CAS  Google Scholar 

  6. Boveri, T. Zellen-Studien Vol. H.4 c.2. (G. Fischer, Jena; 1900).

    Google Scholar 

  7. Chretien, D., Buendia, B., Fuller, S. D. & Karsenti, E. J. Struct. Biol. 120, 117–133 (1997).

    Article  CAS  Google Scholar 

  8. Moritz, M., Braunfeld, M. B., Sedat, J. W., Alberts, B. & Agard, D. A. Nature 378, 638–640 (1995).

    Article  CAS  Google Scholar 

  9. Vogel, J. M., Stearns, T., Rieder, C. L. & Palazzo, R. E. J. Cell Biol. 137, 193–202 (1997).

    Article  CAS  Google Scholar 

  10. Schnackenberg, B. J., Khodjakov, A., Rieder, C. L. & Palazzo, R. E. Proc. Natl Acad. Sci. USA 95, 9295–9300 (1998).

    Article  CAS  Google Scholar 

  11. Dictenberg, J. B. et al. J. Cell Biol. 141, 163–174 (1998).

    Article  CAS  Google Scholar 

  12. Ou, Y. & Rattner, J. B. Cell Motil. Cytoskel. 47, 13–24 (2000).

    Article  CAS  Google Scholar 

  13. Ou, Y. Y., Zhang, M., Chi, S., Matyas, J. R. & Rattner, J. B. Cell Motil. Cytoskel. 55, 125–133 (2003).

    Article  Google Scholar 

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  1. Jens Lüders is in the Cell and Developmental Biology Programme, Institute for Research in Biomedicine, Baldiri i Reixac 10, 08028 Barcelona, Spain,

    Jens Lüders

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  1. Jens Lüders
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Correspondence to Jens Lüders.

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Lüders, J. The amorphous pericentriolar cloud takes shape. Nat Cell Biol 14, 1126–1128 (2012). https://doi.org/10.1038/ncb2617

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