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A cellular sense of touch

Nature Cell Biology volume 14, pages 902–903 (2012)Cite this article

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How cells sense and respond to physical forces is an area of intense investigation, which poses significant challenges for in vitro experiments and even greater obstacles for in vivo studies. Analyses of integrin complex dynamics in Drosophila melanogaster now provide evidence that altering mechanical force modulates the stability of integrin adhesion in vivo.

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Figure 1: Mechanical forces regulate integrin turnover rate.

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Authors and Affiliations

  1. Li He is at the Department of Genetics, Harvard Medical School, Boston, Massachusetts, 02115, USA,

    Li He

  2. Denise Montell is at the Department of Biological Chemistry and Center for Cell Dynamics, Johns Hopkins School of Medicine, 725 North Wolfe Street, Baltimore, Maryland 21205, USA,

    Denise Montell

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  1. Li He
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  2. Denise Montell
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Correspondence to Li He or Denise Montell.

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The authors declare no competing financial interests.

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He, L., Montell, D. A cellular sense of touch. Nat Cell Biol 14, 902–903 (2012). https://doi.org/10.1038/ncb2572

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