In a large-scale analysis, the effects of DNA damage on the levels and localization of almost every protein in an organism have now been tracked in living cells. It is shown that that although many proteins change their position or concentration, they rarely do both.
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Thorpe, P., Rothstein, R. Visualizing global effects of the DNA damage response. Nat Cell Biol 14, 900–901 (2012). https://doi.org/10.1038/ncb2571
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DOI: https://doi.org/10.1038/ncb2571
