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Cdt1 throws kinetochore–microtubule attachments for a loop

Nature Cell Biology volume 14, pages 561–563 (2012)Cite this article

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The Ndc80 complex links spindle microtubules to the kinetochore to ensure the proper segregation of chromosomes during mitosis. Analysis of the replication licensing factor Cdt1 during mitosis now reveals a cooperative role with the Ndc80 complex in establishing stable microtubule attachments to the spindle.

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Figure 1: The role of the Ndc80 complex in kinetochore and spindle–microtubule attachments.

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Authors and Affiliations

  1. Daniel R. Matson and P. Todd Stukenberg are at the Department of Biochemistry and Molecular Genetics, University of Virginia School of Medicine, Charlottesville, Virginia 22908, USA,

    Daniel R. Matson & P. Todd Stukenberg

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  1. Daniel R. Matson
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  2. P. Todd Stukenberg
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Correspondence to P. Todd Stukenberg.

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The authors declare no competing financial interests.

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Matson, D., Stukenberg, P. Cdt1 throws kinetochore–microtubule attachments for a loop. Nat Cell Biol 14, 561–563 (2012). https://doi.org/10.1038/ncb2513

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