In Nishiya et al. (Nature Cell Biol. 7, 343; 2005), the text on page 349 should have read “Additionally, Arf6 can activate phosphatidylinositol 4-phosphate 5-kinases39,40, increasing phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2) formation. Because PtdIns(4,5)P2 is a precursor of PtdIns(3,4,5)P3 — a phospholipid that stimulates several known Rac-GEFs such as Vav41, PIX42 and Tiam1 (ref. 43) — changes in PtdIns(4,5)P2 production might also contribute to the crosstalk between Arf6 and Rac” rather than referring to PtdIns(3,4,5)P2. This has now been corrected online.