Nature Cell Biol. 10, 1291–1300 (2008); published online 19 October 2008; corrected after print 28 October 2008

In the version of this article initially published, the order of the labels siRNA cyclophilin B and siRNA SUZ12 in figure 5 and GAL4-EZH2WT and GAL4-EZH2ΔSET in Figure 7a were reversed. The corrected panels are shown below. These errors have also been corrected in the HTML and PDF versions of the article.