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There goes the neighbourhood: Eps8 joins the barbed-end crowd

The finding that Eps8 caps the barbed ends of actin filaments adds to the growing list of factors responsible for controlling the dynamics of actin polymerization. The requirements for these capping proteins may vary in each cellular context, but EPS-8 seems to be critical during intestinal morphogenesis in the worm.

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Figure 1: Anatomy of human EPS8 protein.
Figure 2: A complex tale of Abi1-containing complexes.

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Higgs, H. There goes the neighbourhood: Eps8 joins the barbed-end crowd. Nat Cell Biol 6, 1147–1149 (2004). https://doi.org/10.1038/ncb1204-1147

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