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Lipid droplets highjack SNAREs

Nature Cell Biology volume 9, pages 1219–1220 (2007)Cite this article

Most intracellular organelles are surrounded by a lipid bilayer and require specialized machinery for membrane fusion. Remarkably, lipid droplets, which contain a hydrophobic core and a monolayer of membrane lipids, can sequester distinct components of this fusion machinery and thereby downregulate certain types of exocytosis.

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Figure 1: SNAP-23 sequestration by lipid droplets blocks exocytosis of glucose transporters.

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  1. Thomas H. Söllner is at the Biochemistry Center, University of Heidelberg, Im Neuenheimer Feld 345, 69120 Heidelberg, Germany. thomas.soellner@bzh.uni-heidelberg.de,

    Thomas H. Söllner

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  1. Thomas H. Söllner
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Söllner, T. Lipid droplets highjack SNAREs. Nat Cell Biol 9, 1219–1220 (2007). https://doi.org/10.1038/ncb1107-1219

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