The self-perpetuating amyloid isoform, or prion, of the yeast translation termination factor eRF3 modulates programmed translational frameshifting that controls a regulatory circuit determining the polyamine levels in a yeast cell. But it is still unclear whether this effect is adaptive or pathological.
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Chernoff, Y. Prion: disease or relief?. Nat Cell Biol 10, 1019–1021 (2008). https://doi.org/10.1038/ncb0908-1019
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DOI: https://doi.org/10.1038/ncb0908-1019
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