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Prion: disease or relief?

Nature Cell Biology volume 10, pages 10191021 (2008) | Download Citation

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The self-perpetuating amyloid isoform, or prion, of the yeast translation termination factor eRF3 modulates programmed translational frameshifting that controls a regulatory circuit determining the polyamine levels in a yeast cell. But it is still unclear whether this effect is adaptive or pathological.

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Affiliations

  1. Yury O. Chernoff is at the School of Biology and Institute for Bioengineering and Bioscience, Georgia Institute of Technology, 310 Ferst Drive, Atlanta, GA 30332-0230, USA.  yury.chernoff@biology.gatech.edu

    • Yury O. Chernoff

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DOI

https://doi.org/10.1038/ncb0908-1019

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