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Neural stem cells: guardians of the brain

Nature Cell Biology volume 9, pages 1031–1034 (2007)Cite this article

Toll-like receptors participate in the inflammatory response and are now shown to act in neural precursor cells to regulate adult hippocampal neurogenesis. The dialogue between inflammatory components and neural precursor cells might have important consequences for central nervous system homeostasis and repair.

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Figure 1: Signalling pathways induced by TLR activation in NPCs.
Figure 2: A 'brain-defence programme'.

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Authors and Affiliations

  1. Gianvito Martino and Stefano Pluchino are in the Neuroimmunology Unit – DIBIT, and Institute of Experimental Neurology (InSpe), San Raffaele Scientific Institute, via Olgettina 58, I-20132, Milan, Italy. martino.gianvito@hsr.it,

    Gianvito Martino & Stefano Pluchino

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  1. Gianvito Martino
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  2. Stefano Pluchino
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Martino, G., Pluchino, S. Neural stem cells: guardians of the brain. Nat Cell Biol 9, 1031–1034 (2007). https://doi.org/10.1038/ncb0907-1031

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